Leucas aspera

Family: Lamiaceae

Synonyms

Family Synonyms

Common Names

Bengali/Vernacular Name: Donkolos, Shetadrone, ChhotoHalkusha. Dulfi. Tribal Name: Pi Tung Chang, Pai Thung Sa (Marma).

Local Availability

Dhaka, Chittagong and Chittagong Hill Tracts in fallow lands

Worldwide Availability

The plant is commonly found throughout India and the Philippines as well as the plains of Mauritius and Java. In India and the Philippines, it is a very common weed

Botanical Description 34

Leucas aspera is an annual, branched, herb erecting to a height of 15-60 cm with stout and hispid acutely quadrangular stem and branches. Leaves are sub-sessile or shortly petiolate, linear or linearl

Common Ethnobotanical Use 35

The plant is used traditionally as an antipyretic and insecticide. Flowers are valued as stimulant, expectorant, aperient, diaphoretic, insecticide and emmenagogue. Leaves are considered useful in chronic rheumatism, psoriasis and other chronic skin eruptions. Bruised leaves are applied locally in snake bites

Chemical Constituents

Compound Name Compound in Plant Parts Reference
LimoneneLeaf; Aerial2, 3
alpha-TerpineolAerial3
EugenolAerial3
beta-Caryophyllene Leaf; Flower; Aerial1, 2, 3
OctadecaneLeaf2
EicosaneLeaf2
StigmasterolRoot8
Hexadecanoic acidLeaf; Seed1, 18, 21
beta-sitosterolRoot; Whole Plant; Shoot; Aerial8, 15, 7, 17, 21
Nonanoic acidLeaf2
Linoleic acidSeed21, 18
beta-FarneseneAerial3
NerolidolLeaf1
(2E,6E)-FarnesolLeaf2
Octadecanoic acidSeed21, 18
gamma-TerpineneAerial3
MentholLeaf2, 21, 23
4-TerpineolAerial3
Methyl salicylateAerial3
n-DodecaneLeaf; Flower2
DecanalAerial3
(E)-2-decenalLeaf2
n-TridecaneLeaf; Flower; Aerial2, 3
beta-BourboneneAerial3
beta-ElemeneAerial3
n-TetradecaneLeaf2
DodecanalLeaf2
beta-GurjuneneAerial3
alpha-HumuleneLeaf; Aerial1, 2, 3
beta-SelineneAerial3
n-PentadecaneFlower2
Caryophyllene oxideLeaf; Aerial1, 3, 24
n-HexadecaneFlower2
Epi-alpha-bisabololAerial3
CampesterolRoot8
Oleanolic acidWhole Plant8, 15
n-Hexacosan-1-ol21, 19
OctacosaneLeaf2
n-Octanoic acidLeaf2
SqualeneLeaf1
ChrysoeriolWhole Plant11
ThymineLeaf1
Linolenic acidSeed21, 18
Oleic acidSeed21, 18
GlycerolLeaf1
Lauric acidLeaf1
gamma-SitosterolAerial21, 16, 19
AcacetinWhole Plant11
1,1,3-Triethoxy propaneLeaf1
2,3-Dihydro-3,5-dihydroxy-6-methyl-4H-pyran-4-oneLeaf1
beta-PineneLeaf; Aerial2, 3
alpha-PineneAerial3
MethyleugenolAerial3
OcimeneLeaf; Aerial2, 3
CampheneAerial3
TricycleneAerial3
TerpinoleneAerial3
alpha-BergamoteneAerial3
cis-JasmoneAerial3
cis-beta-OcimeneAerial3
2-Furancarboxaldehyde, 5-(hydroxymethyl)-Leaf1
4-((1E)-3-Hydroxy-1-propenyl)-2-methoxyphenolLeaf1
Myristic acidLeaf1
DotriacontanolShoot10, 22
alpha-SelineneAerial3
Benzyl benzoateAerial3
ApigeninWhole Plant11
Diethyl pthalateLeaf1
HeptacosaneLeaf2
alpha-PhellandreneAerial3
PhytolLeaf1
alpha-ThujeneLeaf; Aerial2, 3, 21, 23
Ursolic AcidWhole Plant8, 15
Decanoic acidLeaf2
1-Octen-3-olAerial3
PhenylacetaldehydeLeaf1
Di-(2-methylpropyl) phthalateLeaf1
o-CymeneAerial3
n-DecaneFlower2
n-TetradecanolFlower2
3-OctanolAerial3
(Z,E)-alpha-FarneseneLeaf2, 21, 23
beta-ChamigreneAerial3
KhusinolAerial3
(E)-NerolidolLeaf2, 24
alpha-BisabololAerial3
Selin-11-en-4-alpha-olAerial3
(E)-2-nonenalLeaf2
PulegoneAerial3
Methyl linolenateLeaf1
Maslinic acidWhole Plant9
Pentyl propanoateFlower2
1-TrideceneLeaf; Flower2
StearaldehydeLeaf2
1-(3 methyl butyryl) pyrrolidineLeaf1
4H-Pyran-4-one,3,5-dihydroxy-2- methylLeaf1
AzuleneLeaf1
4-Hydroxy-2-methoxycinnamaldehydeLeaf1
Baicalein-7-O-beta-D-glucuronide (baicalin)Flower4, 5
Isoamyl propionateFlower2
5,7-Dihydroxy-2-[14-methoxy-15-propyl phenyl]-4H-chromen-4-one (Leucasin)Leaf6
28-Hydroxypentatriacontan-7-oneShoot7
5-AcetoxytriacontaneShoot7, 22
Leucolactone (3beta,16alpha-dihydroxyoleanan-28→13beta-olide)Root8
Leucasperone AWhole Plant9
Leucasperone BWhole Plant9
Leucasperol AWhole Plant9
Leucasperol BWhole Plant9
Leucasperoside AWhole Plant9
Leucasperoside BWhole Plant9
Leucasperoside CWhole Plant9
AsperphenamateWhole Plant9
(-)-IsololiolideWhole Plant9
1-Hydroxytetratriacontan-4-oneShoot10
32-Methyltetratriacontan-8-olShoot10
Nectandrin BWhole Plant11
meso-Dihydroguaiaretic acidWhole Plant11
MacelignanWhole Plant11
Myristargenol BWhole Plant11
Machilin CWhole Plant11
(-)-ChicanineWhole Plant11
(7R,8R)-licarin AWhole Plant11
NonatriacontaneShoot21, 20
32-Methyltetratriacontane22
BaicaleinFlower5
Bornyl acetateAerial3
1,7-di-epi-alpha-CedreneAerial3
BicyclovetivenolAerial3
NicotineAerial12
alpha-SitosterolAerial21, 17
(rel 5S,6R,8R,9R,10S,13S,15S,16R)-6-acetoxy-9,13;15,16-diepoxy-15-hydroxy-16-methoxylabdaneWhole Plant13
(rel 5S,6R,8R,9R,10S,13S,15R,16R)-6-acetoxy-9,13;15,16-diepoxy-15-hydroxy-16-methoxylabdaneWhole Plant13
Apigenin-7-O-(6″-O-E-caffeoyl)-beta-D-glucopyranosideFlower14
7-Hydroxydotriacontan-2-oneShoot7
LinifoliosideWhole Plant9
erythro-2-(4-allyl-2,6-dimethoxyphenoxy)-1-(4-hydroxy-3-methoxyphenyl)propan-1-olWhole Plant11
4-(24'-hydroxy-1'oxo-5'-n-propyltetracosanyl)-phenolShoot20, 21, 22

Pharmacological Evidence

Plants Parts Extract Type Activity Reference
Aerial
Methanol Antiulcerant 25
Ethyl Acetate Dalton's Ascites Lymphoma 33
Flower
Methanol Antibacterial 27
Leaf
Ethanol CNS Depressant 26
Methanol Antifungal 30
Root
Ethanol Analgesic 28
Ethanol CNS Depressant 32
Whole Plant
Petroleum Ether; Ethanol Analgesic 29
Ethanol; Aqueous Antiinflammatory 29
Methanol Antidiabetic 31

References

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